Presentations and speakers
The following talks were presented at the Legacy of START confrerence, 6-8 October 2022, Cape Town.
| Presentation | Speaker | Affiliation |
| Synchrotron techniques at Diamond Light Source | Gwyndaf Evans | Diamond Light Source, United Kingdom |
| Structural features of heme proteins mediating selective oxyfunctionalization reactions | Dirk Opperman | University of the Free State, South Africa |
| Natural variation in the ‘control loop’ of BVMOAFL210 and its influence on regioselectivity and sulfoxidation | Carmien Tolmie | University of the Free State, South Africa |
| A systems approach to cancer target and drug discovery from aberrant glycosylation in tumourigenesis | Kevin Naidoo | Scientific Computing Research Unit, University of Cape Town, South Africa |
| Structures of bovine glycine N-acyltransferase, key in mammalian homeostasis and African horse sickness virus non-structural protein NS4, an important virulence factor | Albie van Dijk | University of the North West, South Africa |
| Rotavirus vaccine development at the University of the Free State | Trudi O’Neill | University of the North West, South Africa |
| Non-active site mutations in the HIV protease: Diminished drug binding affinity is achieved through modulating the hydrophobic sliding mechanism | Ramesh Pandian | Protein Structure Function Research Unit (PSFRU), University of the Witwatersrand, South Africa |
| Investigating the secreted adhesin EtpA of enterotoxigenic Escherichia coli | Wolf-Dieter Schubert | University of Pretoria, South Africa |
| Countering antimicrobial resistance through chemical manipulation of the pathogen-host interaction | Blake Balcomb | Stellenbosch University, South Africa |
| Rhenium organometallic complexes in proteins for targeted cancer treatment | Francois Jacobs | University of the Free State |
| Starting things | Constantinos Kurt Wibmer | National Institute of Communicable Diseases (NICD), South Africa |
| Successes of START in SA: Structural Biology | Erick Strauss | University of Cape Town, South Africa |
| Cryo-EM reveals mechanisms of angiotensin I-converting enzyme allostery and dimerization | Ed Sturrock | University of Cape Town, South Africa |
| The structure and function of the encapsulin nanocompartment from Mycobacterium tuberculosis | Jeremy Woodward | University of Cape Town, South Africa |
| XChem to COVID Moonshot: a fragment-based drug discovery story. | Lizbé Koekemoer | University of Oxford, United Kingdom |
| Fragment based evaluation of small molecule targeting opportunities in experimentally generated diverse conformations | Mpho Makola | University of Oxford, United Kingdom |
| Cryo Electron Microscopy of Small Membrane Proteins | Andrew Quigley | Membrane Protein Laboratory, Diamond Light Source, United Kingdom |
| Structural Biology in Infectious Disease Research | Thandeka Moyo-Gwete | National Institute of Communicable Diseases (NICD), South Africa |
| An evidence based mechanistic proposal for the cysteine containing amidases | Trevor Sewell | University of Cape Town, South Africa |
| The amidase mechanism: the basis of amide recognition | Stanley Makumire | University of Cape Town, South Africa |
| Engineering nitrilases for enhanced thermostability | Lenye Dlamini | University of Cape Town, South Africa |
| The case for introducing structural biology at the early stages of educational curricula | Addmore Shonhai | University of Venda, South Africa |
| Macromolecular Crystallography at the ESRF | Gordon Leonard | European Synchrotron Radiation Facility (ESRF), France |
| Macromolecular crystallography with synchrotron radiation in Brazil | Igor Polikarpov | University of Sao Paulo, Brazil |
| Recent Advances in the field of Cryo-EM | Gaurav Sharma | Thermo Fisher Scientific, global |
| International Cryo-EM facility at the ESRF, the European Synchrotron | Eaazhisai Kandiah | European Synchrotron Radiation Facility (ESRF), France |
| The importance of automating sample preparation in the democratisation of Structural Biology | Paul Thaw | SPT LabTech, United Kingdom |
| Elucidation of the binding interface and active site of the novel ornithine acyl-ACP N-acyltransferase (OlsB) | Phillip Venter | Watchmaker Genomics, South Africa (and global) |
| SBIO in the Electron Microscope Unit at UCT: our ten-year vision | Jeremy Woodward | University of Cape Town, South Africa |
| A multi-institutional hybrid (on-site and remote) PGDip | Trevor Sewell | University of Cape Town, South Africa |
| Structural Biology in the PSFRU at Wits University: Teaching and Research Strategy | Ramesh Pandian | Protein Structure Function Research Unit (PSFRU), University of the Witwatersrand, South Africa |
| Discussion about the future of Structural Biology in South Africa | Everyone, with Clifford Nxomani National Reseach Foundation of South Africa | Chair: Trevor Sewell |